Thionyl Chloride → HCID 13934695, compound

HRID 1762317Notes

Reaction equation

HRID 1762317 reaction equation
[C:1]([O:4][C:5]1[C:6]([F:16])=[C:7]([CH:11]=[C:12]([F:15])[C:13]=1[F:14])[C:8](O)=[O:9])(=[O:3])[CH3:2].S(Cl)([Cl:19])=O>C1C=CC=CC=1>[C:1]([O:4][C:5]1[C:6]([F:16])=[C:7]([CH:11]=[C:12]([F:15])[C:13]=1[F:14])[C:8]([Cl:19])=[O:9])(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 24386Thionyl Chloride2×HCID 139346943-(Acetyloxy)-2,4,5-trifluorobenzoic acid

Product 1

HCID 13934695HCID 13934695, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent2×

Procedure

In 200 ml of benzene was dissolved 6.10 g (0.026 mole) of 3-acetoxy-2,4,5-trifluorobenzoic acid (V), and to the solution was added 15 ml of thionyl chloride and stirred for 4 hours under reflux. After completion of the reaction, benzene and excess thionyl chloride were completely distilled off under reduced pressure to give 3-acetoxy-2,4,5-trifluorobenzoyl chloride (VI).

Workup

  1. temperatureunder reflux
  2. distillationwere completely distilled off under reduced pressure

Sources & evidence

ORD record
ord-0593fdcae426490c87afc177a59264dc
Source dataset
uspto-grants-1989_05
Patent number
US04831190

Reaction notes

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