反应详情

In a mixture of 0.04 ml of concentrated hydrochloric acid and 11 ml of methanol was dissolved 216 mg of 6-(10-acetoxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone, and the solution was left standing overnight at room temperature. The reaction solution was concentrated under reduced pressure and the concentrate was diluted with water, which was subjected to extraction with ethyl acetate. The extract was washed with a saturated aqueous solution of sodium chloride, then dried. The solvent was evaporated under reduced pressure. The residue was recrystallized from hexane-ethylacetate to yield 115 mg of 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone as orange-colored needles, m.p. 52°-53° C.

1. waitthe solution was left
2. concentrationThe reaction solution was concentrated under reduced pressure
3. additionthe concentrate was diluted with water, which
4. extractionwas subjected to extraction with ethyl acetate
5. washThe extract was washed with a saturated aqueous solution of sodium chloride
6. customdried
7. customThe solvent was evaporated under reduced pressure
8. customThe residue was recrystallized from hexane-ethylacetate