Bromomethyl 4-methoxyphenyl ketone → HCID 178437689, compound

HRID 1762367Notes

Reaction equation

HRID 1762367 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[CH:11][C:6]([C:7](=[O:10])[CH2:8][Br:9])=[CH:5][CH:4]=1.[CH:13](=[N:20][N:21]1[CH:25]=[CH:24][N:23]=[C:22]1[CH2:26][CH3:27])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>C(Cl)CCl>[Br-:9].[CH:13](=[N:20][N+:21]1[CH:25]=[CH:24][N:23]([CH2:8][C:7]([C:6]2[CH:11]=[CH:12][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)=[O:10])[C:22]=1[CH2:26][CH3:27])[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1

Participants

4

Reactant 2

HCID 4965Bromomethyl 4-methoxyphenyl ketoneHCID 540911721-Benzylideneamino-2-ethylimidazole

Product 1

HCID 178437689HCID 178437689, compound

Reagents, catalysts & solvents 1

HCID 111,2-DichloroethaneSolvent

Procedure

2.23 g (10 mmol) of 4-methoxyphenacyl bromide are added to a solution of 1.99 g (10 mmol) of 1-benzylideneamino-2-ethylimidazole in 80 ml of ethylene chloride. The mixture is stirred at 60° for 3 hours, the crystallized-out product is filtered off and washed with ether. There is obtained 1-(benzylideneamino)-2-ethyl-3-(p-methoxyphenacyl)imidazolium bromide of melting point 221°-222°.

Workup

  1. filtrationthe crystallized-out product is filtered off
  2. washwashed with ether

Sources & evidence

ORD record
ord-1211fbf70fd545b4b0241522ef608768
Source dataset
uspto-grants-1989_05
Patent number
US04831151

Reaction notes

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