Formic Acid → HCID 86743052, compound

HRID 1762399Notes

Reaction equation

[CH3:1][N:2]([CH:7]([CH:14]1[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1)[CH:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1)[CH2:3][C:4](O)=O.C(OC(=O)C)(=[O:22])C.[CH:27]([OH:29])=[O:28]>>[CH3:4][CH:3]([C:27]([OH:29])=[O:28])[N:2]([CH:7]([CH:14]1[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1)[CH:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1)[CH:1]=[O:22]

Participants

Reactant 3

HCID 284Formic Acid

HCID 7918Acetic Anhydride

HCID 70393879HCID 70393879, compound

Product 1

HCID 86743052HCID 86743052, compound

Conditions

Temperature: 5 °C

Procedure

143 Parts of methyl N-[(dicyclohexyl)methyl]glycine were added dropwise to 290 parts of formic acid while cooling to 5° C. Subsequently 90 parts of acetic anhydride were added, and the mixture was kept at room temperature for 48 hours. Destillation under vacuo afforded 154 parts of methyl N-[(dicyclohexyl)methyl]-N-formylglycine (int. 2).

Sources & evidence

ORD record: ord-06e0373d2c984ee49ad216fc4d968d72
Source dataset: uspto-grants-1989_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04832732

Reaction notes

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