HCID 20040862, compound → HCID 54360501, compound

HRID 1762455Notes

Reaction equation

HRID 1762455 reaction equation
[CH2:1]([N:5]([CH3:27])[C:6](=[O:26])[CH2:7][CH2:8][CH2:9][N:10]1[CH2:15][CH2:14][N:13](C(OCC2C=CC=CC=2)=O)[CH2:12][CH2:11]1)[CH2:2][CH2:3][CH3:4]>[Pd].C(O)C>[CH2:1]([N:5]([CH3:27])[C:6](=[O:26])[CH2:7][CH2:8][CH2:9][N:10]1[CH2:11][CH2:12][NH:13][CH2:14][CH2:15]1)[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 1

HCID 20040862HCID 20040862, compound

Product 1

HCID 54360501HCID 54360501, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A mixture of the N-n-butyl-N-methyl-4-(4- benzyloxycarbonylpiperazin-1-yl)butyramide thus obtained (0.187 g.), a 10% palladium-on-charcoal catalyst (0.1 g.) and ethanol (5 ml.) was stirred at laboratory temperature under an atmosphere of hydrogen for 22 hours and then filtered and the filtrate was evaporated to dryness. There was thus obtained as an oil N-n-butyl-N-methyl-4-(piperazin-1-yl)butyramide.

Workup

  1. customthus obtained (0.187 g.)
  2. filtrationfiltered
  3. customthe filtrate was evaporated to dryness

Sources & evidence

ORD record
ord-d71e8072a66c43a09d3daab6663f7e3b
Source dataset
uspto-grants-1989_05
Patent number
US04833135

Reaction notes

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