Acetic Acid → HCID 178464550, compound

Participants

Reaction Steps

The product of Stage (i) (1.0 g) was suspended in chloroform (25 ml) and acetic acid (0.5 ml) was added, followed by ethylamine (0.2 g) in chloroform (10 ml). The solution was stirred at room temperature for 3 h. The resulting suspension was collected, washed with diethyl ether (1 l) and dried in vacuo at 20° for 18 h to give a solid (0.5 g) which was recrystallised from methanol-ethyl acetate (1:3) to give the pure title compound as a solid (0.09 g), m.p. 261°-263°

Provenance & Evidence