Hydrochloric Acid → HCID 54398862, compound

HRID 1762497Notes

Reaction equation

HRID 1762497 reaction equation
O1CCCCC1[O:7][CH2:8][CH2:9][N:10]1[CH2:14][CH2:13][C:12](=[CH:15][C:16]2[CH:21]=[C:20]([C:22]([CH3:25])([CH3:24])[CH3:23])[C:19]([OH:26])=[C:18]([C:27]([CH3:30])([CH3:29])[CH3:28])[CH:17]=2)[C:11]1=[O:31].Cl>CO>[OH:7][CH2:8][CH2:9][N:10]1[CH2:14][CH2:13][C:12](=[CH:15][C:16]2[CH:21]=[C:20]([C:22]([CH3:23])([CH3:24])[CH3:25])[C:19]([OH:26])=[C:18]([C:27]([CH3:30])([CH3:29])[CH3:28])[CH:17]=2)[C:11]1=[O:31]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 54093054HCID 54093054, compound

Product 1

HCID 54398862HCID 54398862, compoundYield 62.2%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

300 mg of N-2-(2-tetrahydropyranyloxy)ethyl-3-(3,5-di-tert-butyl-4-hydroxybenzylidene)-2-pyrrolidone was hydrolyzed with hydrochloric acid in methanol according to the procedure of Example 5 to give 150 mg of the title compound.

Sources & evidence

ORD record
ord-4eea62e2270a4f51a78d78befeafc64d
Source dataset
uspto-grants-1989_05
Patent number
US04833160

Reaction notes

Loading…