Potassium Carbonate → HCID 13747688, compound

Participants

Reaction Steps

22.2 g (0.1 mol) of the xanthine from stage (a) are reacted with 16.6 g (0.11 mol) of 1-chloro-5-hydroxy-5-methylhexane (Example 1a) and 15.2 g (0.11 mol) of potassium carbonate in 500 ml of dimethylformamide and the mixture is worked up, under the experimental conditions described in Example 2. The reaction product is purified by column chromatography and finally recrystallized from diisopropyl ether, with the addition of ethyl acetate, at the boiling point.

Provenance & Evidence