Bromide ion → HCID 9904201, Verbindung

HRID 1762552Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1762552
[CH3:1][N:2]1[C:10]2[N:9]=[CH:8][N:7]([CH3:11])[C:6]=2[C:5](=[O:12])[NH:4][C:3]1=[O:13].Cl[CH2:15][CH2:16][CH2:17][CH2:18][C:19]([OH:22])([CH3:21])[CH3:20].CN1C2N=CN(C)C=2C(=O)N(CCCCC(=O)C)C1=O.C[Mg]Cl.[Br-].C(N1C2C(=O)NC(=O)N(C)C=2N=C1)C1C=CC=CC=1>>[OH:22][C:19]([CH3:21])([CH3:20])[CH2:18][CH2:17][CH2:16][CH2:15][N:4]1[C:5](=[O:12])[C:6]2[N:7]([CH3:11])[CH:8]=[N:9][C:10]=2[N:2]([CH3:1])[C:3]1=[O:13]

Komponenten

7

Edukt 6

HCID 259Bromide ionHCID 4740PentoxifyllineHCID 5429TheobromineHCID 6856307-Benzyl-3-methylxanthineHCID 137476791-Chloro-5-hydroxy-5-methylhexaneHCID 178418332HCID 178418332, Verbindung

Produkt 1

HCID 9904201HCID 9904201, Verbindung

Versuchsvorschrift

Alternatively, it was possible, inter alia, to prepare the compound from 3,7-dimethylxanthine and 1-chloro-5-hydroxy-5-methylhexane analogously to Example 2 or 4, from 3,7-dimethyl-1-(5-oxohexyl)-xanthine and methylmagnesium chloride or bromide analogously to Example 9, and from the compound of Example 6 and a methylating agent analogously to Example 3.

Quellen und Nachweise

ORD-Eintrag
ord-11fb17fbfd63459d8b17f8fe2e6e3bf2
Quelldatensatz
uspto-grants-1989_05
Patentnummer
US04833146

Notizen zur Reaktion

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