Bromide ion → 2-{2-[4-(5-fluoropyridin-2-yl)phenyl]-1-hydroxy-1-methylethyl}-N,N-dimethyl-4-[2-methyl-2-(trifluoromethyl)but-3-en-1-yl]-1H-imidazole-1-sulfonamide
Reaction equation
[Br-:1].[CH3:2][Mg+:3].[F:4][c:5]1[cH:6][cH:7][c:8](-[c:11]2[cH:12][cH:13][c:14]([CH2:17][C:18](=[O:19])[c:20]3[n:21]([S:34](=[O:35])(=[O:36])[N:37]([CH3:38])[CH3:39])[cH:22][c:23]([CH2:25][C:26]([CH:27]=[CH2:28])([C:29]([F:30])([F:31])[F:32])[CH3:33])[n:24]3)[cH:15][cH:16]2)[n:9][cH:10]1.[O:40]1[CH2:41][CH2:42][CH2:43][CH2:44]1>>[CH3:2][C:18]([CH2:17][c:14]1[cH:13][cH:12][c:11](-[c:8]2[cH:7][cH:6][c:5]([F:4])[cH:10][n:9]2)[cH:16][cH:15]1)([OH:19])[c:20]1[n:21]([S:34](=[O:35])(=[O:36])[N:37]([CH3:38])[CH3:39])[cH:22][c:23]([CH2:25][C:26]([CH:27]=[CH2:28])([C:29]([F:30])([F:31])[F:32])[CH3:33])[n:24]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-1edf52441a0e40daabb67e08686286a1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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