HRID1762804

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6328

Methyl iodide

CH3I

HCID10942334

Methanol, sodium salt

CH3NaO

结构：CN1CCN(Cc2cnc(S)n2Cc2cc(F)cc(F)c2)CC1

HCID178480840

未命名化合物

PRODUCTS

生成物

结构：CN1CCN(Cc2cncn2Cc2cc(F)cc(F)c2)CC1.CSc1ncc[nH]1

HCID70391373

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

Reaction of 1-(3,5-difluorobenzyl)-5-[(4-methyl-1-piperazinyl)methyl]imidazole-2-thiol prepared as in Example 1 with methyl iodide and sodium methoxide in methanol by known techniques yields 1-(3,5-difluorobenzyl)-5-[(4-methyl-1-piperazinyl)methyl]imidazole-2-methylthioimidazole.