HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 1-(3,5-Difluorobenzyl)-5-[(4-methyl-1-piperazinyl)methyl]imidazole 2-methylthioimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | 1-(3,5-Difluorobenzyl)-5-[(4-methyl-1-piperazinyl)methyl]-2-mercaptoimidazole | HCID 178480840 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1-(3,5-Difluorobenzyl)-5-[(4-methyl-1-piperazinyl)methyl]imidazole 2-methylthioimidazole | HCID 70391373 | — |
Reaction Steps
Reaction of 1-(3,5-difluorobenzyl)-5-[(4-methyl-1-piperazinyl)methyl]imidazole-2-thiol prepared as in Example 1 with methyl iodide and sodium methoxide in methanol by known techniques yields 1-(3,5-difluorobenzyl)-5-[(4-methyl-1-piperazinyl)methyl]imidazole-2-methylthioimidazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04835154 |
| Source dataset | uspto-grants-1989_05 |
| ORD ID | ord-3bc695aabb154fe0813b2552a4442823 |
| Source note | uspto-grants-1989_05 |