Hydrochloric Acid → HCID 178428183, compound

HRID 1762848Notes

Reaction equation

HRID 1762848 reaction equation
C([N:4]1[C:8]2=[CH:9][C:10]3[N:14]=[N:13][NH:12][C:11]=3[CH:15]=[C:7]2[C:6]([CH3:17])([CH3:16])[CH2:5]1)(=O)C.[ClH:18]>>[ClH:18].[ClH:18].[CH3:16][C:6]1([CH3:17])[C:7]2[C:8](=[CH:9][C:10]3[N:14]=[N:13][NH:12][C:11]=3[CH:15]=2)[NH:4][CH2:5]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 178473799HCID 178473799, compound

Product 1

HCID 178428183HCID 178428183, compound

Procedure

0.5 g. of the product of Example 7 is heated under reflux for 2.5 hours with 20 ml. ethanolic hydrogen chloride solution, then allowed to cool and filtered. There is obtained 0.4 g. (70% of theory) of the title compound; m.p. 243°-245° C.

Workup

  1. temperatureunder reflux for 2.5 hours with 20 ml
  2. temperatureto cool
  3. filtrationfiltered
  4. customThere is obtained 0.4 g

Sources & evidence

ORD record
ord-50b6861ba0ff42c1bafcd4807cf529f3
Source dataset
uspto-grants-1989_05
Patent number
US04835167

Reaction notes

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