4-Aminophenol → HCID 12941115, compound

HRID 1762869Notes

Reaction equation

HRID 1762869 reaction equation
[CH:1]1[C:6]([NH2:7])=[CH:5][CH:4]=[C:3]([OH:8])[CH:2]=1.[Br:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][C:15](Cl)=[O:16]>>[Br:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][C:15]([NH:7][C:6]1[CH:5]=[CH:4][C:3]([OH:8])=[CH:2][CH:1]=1)=[O:16]

Participants

3

Reactant 2

HCID 4034-AminophenolHCID 898486-Bromohexanoyl chloride

Product 1

HCID 12941115HCID 12941115, compoundYield 88%

Procedure

was prepared in 88% yield from 148.4 g (1.36 mol) of p-aminophenol and 145 g (0.68 mol) of 6-bromohexanoyl chloride according to the procedure of Example 1, part a, except that the addition was made at ambient temperature and the reaction was refluxed one hour, mp 124°-125° C.

Workup

  1. additionexcept that the addition
  2. customwas made at ambient temperature
  3. temperaturethe reaction was refluxed one hour

Sources & evidence

ORD record
ord-46f4b1df2a0e4e0cb7fbcc0cb7343983
Source dataset
uspto-grants-1989_05
Patent number
US04835180

Reaction notes

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