Diboron → HCID 14500517, compound

HRID 1762876Notes

Reaction equation

HRID 1762876 reaction equation
[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][C:7]([NH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[OH:16])=O.B#B>>[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][NH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[OH:16]

Participants

3

Reactant 2

HCID 6328200DiboronHCID 14500507HCID 14500507, compound

Product 1

HCID 14500517HCID 14500517, compoundYield 81%

Procedure

was prepared in 81% yield from 30.6 g (0.11 mol) of 6-bromo-N-(2-hydroxyphenyl)hexanamide according to the procedure of Example 1, part b, except that the amide was added to the diborane (inverse addition). The product was crystallized from acetonitrile by the addition of chloroform and then ether, mp 124°-126° C.

Workup

  1. customThe product was crystallized from acetonitrile by the addition of chloroform

Sources & evidence

ORD record
ord-e1d6da5a845449b9ae79185e509166b9
Source dataset
uspto-grants-1989_05
Patent number
US04835180

Reaction notes

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