HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 13242194, compound → 2-(Dimethylamino)ethyl 7-hydroxy-1H-indole-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 13242194 | HCID 13242194 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-(Dimethylamino)ethyl 7-hydroxy-1H-indole-2-carboxylate | HCID 13242195 | 56% |
Reaction Steps
Under the conditions of Example 14(C), 9 g of 7-benzyloxyindole-2-carboxylic acid 2-dimethylaminoethyl ester is hydrogenated in a mixture of 50 ml of methanol and 50 ml of tetrahydrofuran and worked up, yielding 3.7 g of 7-hydroxyindole-2-carboxylic acid 2-dimethylaminoethyl ester, mp 149°-152° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04835175 |
| Source dataset | uspto-grants-1989_05 |
| ORD ID | ord-298b8f54f47848a1befd588b9ef66470 |
| Source note | uspto-grants-1989_05 |