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HRID1762953

反应详情

EQUATION

反应方程式

HRID 1762953 的结构方程式

REACTANTS

反应物

2
结构：CCOC(=O)CC(C)(C)NCc1ccccc1
HCID288946

ethyl 3-(benzylamino)-3-methylbutanoate

C14H21NO2

结构：CCOC(=O)c1cc2c(C(=O)CCl)ccc(O)c2[nH]1
HCID13243454

Ethyl 4-(chloroacetyl)-7-hydroxy-1H-indole-2-carboxylate

C13H12ClNO4

PRODUCTS

生成物

1
结构：CCOC(=O)CC(C)(C)N(CC(=O)c1ccc(O)c2[nH]c(C(=O)OCC)cc12)Cc1ccccc1.Cl
HCID70381467

未命名化合物

收率 15.9%

PROCEDURE

实验过程

Under the conditions of Example 28, 2.57 g of 4-chloroacetyl-7-hydroxyindole-2-carboxylic acid ethyl ester is reacted with 2.35 g of 3-benzylamino-3-methylbutyric acid ethyl ester and worked up, yielding 0.75 g of 4-[N-benzyl-N-(2-ethoxycarbonyl-1,1-dimethylethyl)aminoacetyl]-7-hydroxyindole-2-carboxylic acid ethyl ester hydrochloride, decomposition point 210°-212° C.