Water → HCID 86743082, compound

HRID 1762968Notes

Reaction equation

HRID 1762968 reaction equation
[C:1](Cl)(=O)/[CH:2]=C/C(Cl)=O.Cl.Cl.C(OC(=O)[C@H]([CH2:17][CH2:18][CH2:19][CH2:20][NH2:21])N)C.Cl.Cl.[CH2:25]([O:29][C:30](=[O:38])[C@H:31]([CH2:33][CH2:34][CH2:35][CH2:36][NH2:37])[NH2:32])[CH2:26][CH2:27][CH3:28].[OH-:39].[K+].[OH2:41]>C(Cl)Cl>[C:17]([NH2:32])(=[O:41])/[CH:18]=[CH:19]/[C:20]([NH2:21])=[O:39].[CH2:1]([CH:25]([O:29][C:30](=[O:38])[C@H:31]([CH2:33][CH2:34][CH2:35][CH2:36][NH2:37])[NH2:32])[CH2:26][CH2:27][CH3:28])[CH3:2]

Participants

7

Reactant 5

HCID 962WaterHCID 14797Potassium HydroxideHCID 107468Lysine ethyl ester dihydrochlorideHCID 5325504Fumaryl chlorideHCID 22817831butyl L-lysinate dihydrochloride

Product 1

HCID 86743082HCID 86743082, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

1.52 g of fumaryl chloride in 200 ml of methylene chloride are polycondensed, analogously to Example 2, with 2.47 g of lysine ethyl ester dihydrochloride and 2.75 g of lysine butyl ester dihydrochloride in 200 ml of water which contains 5.5 g of potassium hydroxide. 2.5 g (71% of theory) of white, fiber-like copolycondensate are obtained.

Workup

  1. custom2.5 g (71% of theory) of white, fiber-like copolycondensate are obtained

Sources & evidence

ORD record
ord-8fc2749bc2ca49ea881cfab1bff90888
Source dataset
uspto-grants-1989_05
Patent number
US04835248

Reaction notes

Loading…