Water → HCID 86743084, compound

HRID 1762969Notes

Reaction equation

HRID 1762969 reaction equation
[C:1]([OH:8])(=[O:7])/[CH:2]=[CH:3]/[C:4]([OH:6])=[O:5].O[N:10]1[C:14]2C=CC=C[C:13]=2NN1O.[C:20](OCCN)(=O)[CH2:21]CC([O-])=O.[OH2:31].C[N:33]1[CH2:37][CH2:36][CH2:35][C:34]1=[O:38]>>[C:34]([NH2:10])(=[O:38])/[CH:35]=[CH:36]/[C:37]([NH2:33])=[O:31].[C:1]([OH:8])(=[O:7])[CH2:2][CH2:3][C:4]([OH:6])=[O:5].[CH2:13]=[CH2:14].[CH2:20]=[CH2:21]

Participants

5

Reactant 4

HCID 962WaterHCID 13387N-methyl-2-pyrrolidoneHCID 20040010HCID 20040010, compoundHCID 86743085HCID 86743085, compound

Product 1

HCID 86743084HCID 86743084, compound

Procedure

1.75 g of di-N-hydroxybenzotriazole fumarate and 1.02 g of 2-aminoethyl succinate in 10 ml of dry N-methylpyrrolidone are stirred at room temperature for 48 hours with exclusion of moisture. The reaction mixture is subsequently added dropwise to 100 ml of water, and the polycondensate is centrifuged off and, after washing with hot water, dried in vacuo at 60° C.

Workup

  1. washafter washing with hot water
  2. customdried in vacuo at 60° C.

Sources & evidence

ORD record
ord-11be93e3e72f47539a1ca4ced2679f64
Source dataset
uspto-grants-1989_05
Patent number
US04835248

Reaction notes

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