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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1762976Generated: October 25, 2026

3-(Methylsulfanyl)propanenitrile → HCID 178458073, compound

https://huagongshe.com/reaction/1762976

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Methylsulfanyl)propanenitrileHCID 548386—
ReactantHCID 178418935HCID 178418935—
ProductHCID 178458073HCID 178458073—

Reaction Steps

N-sulfamyl-acrylamidine was prepared by a four-step procedure from 3-(methylthio)-propionitrile, with an extremely low (5.5%) yield in several days. The products of the subsequent steps, including famotidine, were isolated by column chromatography.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04835281
Source datasetuspto-grants-1989_05
ORD IDord-09fcdf6f02f84672bde87c942a1f3963
Source noteuspto-grants-1989_05