Acetic Acid → HCID 13687205, compound

HRID 1762992Notes

Reaction equation

HRID 1762992 reaction equation
[Cl:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([NH:11][NH2:12])=[C:4]([F:13])[CH:3]=1.[C:14]([CH:17]1[CH2:22][CH2:21][CH2:20][CH2:19][C:18]1=O)(=O)[CH3:15].C(O)(=O)C>C1(C)C(C)=CC=CC=1>[Cl:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([N:11]2[C:14]([CH3:15])=[C:17]3[C:18]([CH2:19][CH2:20][CH2:21][CH2:22]3)=[N:12]2)=[C:4]([F:13])[CH:3]=1

Participants

5

Reactant 3

HCID 176Acetic AcidHCID 134002-AcetylcyclohexanoneHCID 13629447HCID 13629447, compound

Product 1

HCID 13687205HCID 13687205, compoundYield 38.2%

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

In the same manner as in Example 6 but using 4-chloro-2-fluoro-5-nitrophenylhydrazine (4 g), 2-acetylcyclohexanone (2.8 g), a catalytic amount of acetic acid and xylene (10 ml), there was produced 2.3 g of 2-(4-chloro-2-fluoro-5-nitrophenyl)-3-methyl-4,5,6,7-tetrahydro-2H-indazole. m.p., 143°-144° C.

Sources & evidence

ORD record
ord-4621fa51075d44f8ae6c7183816db8b4
Source dataset
uspto-grants-1989_05
Patent number
US04835286

Reaction notes

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