HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aminopyrazine → N-(2-pyrazinyl)-1-(4-methoxybenzyl)-1H-tetrazole-5-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aminopyrazine | HCID 78747 | — |
| Reactant | 1-(4-methoxybenzyl)-1H-tetrazole-5-carbonyl chloride | HCID 20463870 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-(2-pyrazinyl)-1-(4-methoxybenzyl)-1H-tetrazole-5-carboxamide | HCID 20310358 | — |
Reaction Steps
1-(4-Methoxybenzyl)-1H-tetrazole-5-carbonyl chloride is reacted in methylene chloride with 2-aminopyrazine to obtain N-(2-pyrazinyl)-1-(4-methoxybenzyl)-1H-tetrazole-5-carboxamide. The protected intermediate is deprotected and worked up by the techniques described in Example 1 to yield the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04112094 |
| Source dataset | uspto-grants-1978_09 |
| ORD ID | ord-05cc6f0f457f4585aea8d73efa089f18 |
| Source note | uspto-grants-1978_09 |