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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1763477Generated: October 31, 2026

Trimethyl phosphite → Dimethyl (Phthalimidomethyl)Phosphonate

https://huagongshe.com/reaction/1763477

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrimethyl phosphiteHCID 8472—
Reactant1H-Isoindole-1,3(2H)-dione, 2-(2-bromoethyl)-HCID 11325—
ReactantTriethyl phosphiteHCID 31215—
Reactant1H-Isoindole-1,3(2H)-dione, 2-(bromomethyl)-HCID 79244—
ProductDimethyl (Phthalimidomethyl)PhosphonateHCID 2773790—

Reaction Steps

Reaction of N-bromomethylphthalimide with trimethyl phosphite as described in Example 18 for N-(2-bromoethyl)phthalimide and triethyl phosphite gives dimethyl phthalimidomethylphosphonate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04112086
Source datasetuspto-grants-1978_09
ORD IDord-5c70dcfee14849339d739b3b13e04deb
Source noteuspto-grants-1978_09