Sodium Hydroxide → HCID 54167400, compound

Participants

Reaction Steps

A mixture of o-(5-phenyl-3-isoxazolyl)benzyl acetate, 35.2 ml. (0.352 mole) of 1 N sodium hydroxide solution and 95 ml. of ethanol is stirred for 4 days at room temperature. The ethanol is removed in vacuo and the aqueous material extracted with methylene chloride. The methylene chloride is washed with water, dried over anhydrous magnesium sulfate, filtered and evaporated in vacuo. The residue is crystallized from ether/petroleum ether to give o-(5-phenyl-3-isoxazolyl) benzyl alcohol; m.p. 68° to 70° C.

Provenance & Evidence