HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Butanol → HCID 9971560, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Butanol | HCID 263 | — |
| Reactant | Propionylhydrazine | HCID 79890 | — |
| Reactant | 3-Chloro-6-[3-(trifluoromethyl)phenyl]pyridazine | HCID 12449552 | — |
| Solvent | Chloroform hexane | HCID 21585165 | — |
| Product | HCID 9971560 | HCID 9971560 | — |
Reaction Steps
A mixture of 5.0 g. of 3-chloro-6-(α,α,α-trifluoro-m-tolyl)pyridazine, 3.40 g. of propionic acid hydrazide and 100 ml. of n-butanol is refluxed for 48 hr. The solvent is removed under vacuum and the residue dissolved in chloroform. The solution is passed through a column of hydrous magnesium silicate and the eluent concentrated to give 3.0 g. of crystals (from CHCl3 -hexane), m.p. 183°-185° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04112095 |
| Source dataset | uspto-grants-1978_09 |
| ORD ID | ord-d8f9abc52a744fbfb1b5aa0ed34737a7 |
| Source note | uspto-grants-1978_09 |