Hydrazinecarboxaldehyde → HCID 20310359, compound

HRID 1763628Notes

Reaction equation

HRID 1763628 reaction equation
CC1C=CC(Cl)=CC=1C=O.Cl[C:12]1[N:13]=[N:14][C:15]([C:18]2[CH:23]=[C:22]([Cl:24])[CH:21]=[CH:20][C:19]=2[CH3:25])=[CH:16][CH:17]=1.[CH:26]([NH:28][NH2:29])=O>C(O)CCC>[CH3:25][C:19]1[CH:20]=[CH:21][C:22]([Cl:24])=[CH:23][C:18]=1[C:15]1[CH:16]=[CH:17][C:12]2[N:13]([CH:26]=[N:28][N:29]=2)[N:14]=1

Participants

5

Reactant 3

HCID 12229HydrazinecarboxaldehydeHCID 123475655-Chloro-2-methylbenzaldehydeHCID 20310362HCID 20310362, compound

Product 1

HCID 20310359HCID 20310359, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

As described in Example 35, 2-methyl-5-chlorobenzaldehyde is converted to 3-chloro-6-(2-methyl-5-chlorophenyl)pyridazine. A mixture of the preceding compound and formylhydrazine in n-butanol is refluxed for 24 hours to give the product of the example.

Workup

  1. temperatureis refluxed for 24 hours
  2. customto give the product of the example

Sources & evidence

ORD record
ord-22ff91238a354d2bb2b52a9689da92bd
Source dataset
uspto-grants-1978_09
Patent number
US04112095

Reaction notes

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