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HRID1763664

反应详情

EQUATION

反应方程式

HRID 1763664 的结构方程式

REACTANTS

反应物

2
结构：O=S(Cl)Cl
HCID24386

Thionyl chloride

Cl2OS

结构：CN(C)CCC=C1c2ccccc2C=Cn2cc(C(=O)O)cc21
HCID54191185

未命名化合物

PRODUCTS

生成物

1
结构：CN(C)CCC=C1c2ccccc2C=Cn2cc(C(=O)Cl)cc21
HCID54024205

未命名化合物

PROCEDURE

实验过程

2-Carboxy-11-(3-dimethylaminopropylidene)-11H-pyrrolo[2,1-b][3]benzazepine (99 mmoles) in 100 ml. of thionyl chloride is refluxed for 15 minutes. The volatiles are removed under vacuum and the residue is triturated in ether. Filtration and air drying yields 2-chlorocarbonyl-11-(3-dimethylaminopropylidene)-11H-pyrrolo[2,1-b][3]benzazepine.

WORKUP

后处理

  1. customThe volatiles are removed under vacuum
  2. customthe residue is triturated in ether
  3. filtrationFiltration and air
  4. customdrying