HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2-chlorocarbonyl-11-(3-dimethylaminopropylidene)-11H-pyrrolo[2,1-b][3]benzazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-carboxy-11-(3-dimethylaminopropylidene)-11H-pyrrolo[2,1-b][3]benzazepine | HCID 54191185 | — |
| Product | 2-chlorocarbonyl-11-(3-dimethylaminopropylidene)-11H-pyrrolo[2,1-b][3]benzazepine | HCID 54024205 | — |
Reaction Steps
2-Carboxy-11-(3-dimethylaminopropylidene)-11H-pyrrolo[2,1-b][3]benzazepine (99 mmoles) in 100 ml. of thionyl chloride is refluxed for 15 minutes. The volatiles are removed under vacuum and the residue is triturated in ether. Filtration and air drying yields 2-chlorocarbonyl-11-(3-dimethylaminopropylidene)-11H-pyrrolo[2,1-b][3]benzazepine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04112112 |
| Source dataset | uspto-grants-1978_09 |
| ORD ID | ord-90b53b5b116b475b9cc4b5496ef3f5ba |
| Source note | uspto-grants-1978_09 |