N-Hydroxysuccinimide → HCID 70617506, compound

Participants

Reaction Steps

A 4.6 gram portion of N-hydroxysuccinimide and 5.5 ml. of 2,2,2-trichloroethylchloroformate in 30 ml. of dry pyridine is reacted as described in Example 2. The product is recrystallized from diethyl ether giving 2,2,2-trichloroethyl carbonate succinimide. A 400 mg. portion of this product and 300 mg. of trans-BM123γ are reacted as described in Example 1 giving 273.9 mg. of trichloroacetyl-trans-BM123γ.

Provenance & Evidence