HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 178465181, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Reactant | HCID 178465168 | HCID 178465168 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178465181 | HCID 178465181 | — |
Reaction Steps
A solution of 8.7 g. of Nα -benzyloxycarbonyl-L-arginyl-L-proline N-ethylamide hydrochloride in 100 ml. of methanol is stirred with 500 mg. of 20% palladium on carbon under one inch water pressure of hydrogen for three hours. The catalyst is removed by filtration and the filtrate evaporated under reduced pressure and at 35°-40° C. The residual foam is used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04111923 |
| Source dataset | uspto-grants-1978_09 |
| ORD ID | ord-d822306ecf144b95be274ece79f8a49b |
| Source note | uspto-grants-1978_09 |