Acetate → HCID 178465156, compound

Participants

Reaction Steps

A solution of 100 mg. of Nα -benzyloxycarbonyl-L-glutaminyl-L-tryptophyl-L-seryl-L-tyrosyl-D-alanyl-L-leucyl-L-arginyl-L-proline N-ethylamide, hydrochloride in a minimal amount of water, 40 to 50 ml., is put on a column of Dowex 1×2 (acetate form) 1.2×37 cm. The material is then eluted with water (150 ml.) and the fractions lyophilized and the Nα -benzyloxycarbonyl-L-glutaminyl-L-tryptophyl-L-seryl-L-tyrosyl-D-alanyl-L-leucyl-L-arginyl-L-proline N-ethylamide acetic acid salt examined by ultraviolet in methanol (λmax 280 E11 56.3) and for chloride. Analysis indicates an acetate salt with 2 CH3COOH and 5 H2O in the molecular formula.

Provenance & Evidence