Imidazole → HCID 53784482, compound

HRID 1763753Notes

Reaction equation

HRID 1763753 reaction equation
[CH:1](=[CH:8][C:9]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4]C=1.[NH:17]1[CH:21]=[CH:20][N:19]=[CH:18]1.[C:22](=S)=S>>[C:1]1([C:8]([N:17]2[CH:21]=[CH:20][N:19]=[CH:18]2)([CH3:22])[C:9]([C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)=[O:10])[CH:2]=[CH:7][CH:6]=[CH:5][CH:4]=1

Participants

4

Reactant 3

HCID 795ImidazoleHCID 6348Carbon DisulfideHCID 7189Cinnamoylbenzene

Product 1

HCID 53784482HCID 53784482, compound

Procedure

Benzalacetophenone (4.2 g, 0.02 mol) and imidazole (1.34 g, 0.02 mol) were warmed over a flame for 30 minutes. After cooling to room temperature, the oil was treated with carbon disulphide to give, as colourless crystals, 2-phenyl-2-(imidazol-1-yl) propiophenone (compound 3) m.p. 75°-76° C.

Workup

  1. temperaturea flame for 30 minutes

Sources & evidence

ORD record
ord-712292c363ed45108f93210b66070259
Source dataset
uspto-grants-1978_09
Patent number
US04113465

Reaction notes

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