Trifluoroacetic acid → HCID 178477074, compound

HRID 1763830Notes

Reaction equation

[C:1]([S:4][CH2:5][CH:6]([CH2:21][CH2:22][CH2:23][NH:24]C(OCC1C=CC(OC)=CC=1)=O)[C:7]([NH:9][C@H:10]([C:18]([OH:20])=[O:19])[CH2:11][CH2:12][CH2:13][NH:14][C:15](=[NH:17])[NH2:16])=[O:8])(=[O:3])[CH3:2].[F:37][C:38]([F:43])([F:42])[C:39]([OH:41])=[O:40]>>[F:37][C:38]([F:43])([F:42])[C:39]([OH:41])=[O:40].[C:1]([S:4][CH2:5][CH:6]([CH2:21][CH2:22][CH2:23][NH2:24])[C:7]([NH:9][C@H:10]([C:18]([OH:20])=[O:19])[CH2:11][CH2:12][CH2:13][NH:14][C:15](=[NH:16])[NH2:17])=[O:8])(=[O:3])[CH3:2]

Participants

Reactant 2

HCID 6422Trifluoroacetic acid

HCID 178491554HCID 178491554, compound

Product 1

HCID 178477074HCID 178477074, compound

Procedure

A solution of Nα -[2-acetylthiomethyl-5-(p-methoxybenzyloxycarbonylamino)pentanoyl]-L-arginine (1 g) in trifluoroacetic acid (10 ml) is stored at room temperature for fifteen minutes, and then concentrated to dryness in vacuo to yield Nα -(2-acetylthiomethyl-5-aminopentanoyl)-L-arginine trifluoroacetate.

Workup

concentrationconcentrated to dryness in vacuo

Sources & evidence

ORD record: ord-b690f52b23314e1099333f1e9651f2bb
Source dataset: uspto-grants-1978_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04113715

Reaction notes

Loading…