HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → Clemeprol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | HCID 11064260 | HCID 11064260 | — |
| Product | Clemeprol | HCID 71985 | 37% |
Reaction Steps
p-Chlorophenyl-phenylacetaldehyde (5 68g) was reacted with dimethylsulphoxonium methylide and the crude epoxide obtained further reacted with dimethylamine in ethanol by the procedures described in Example 8 to give 3-dimethylamino- 1-p-chlorphenyl-1-phenyl-propan-2-ol (2.6g., 37% from aldehyde) as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04113972 |
| Source dataset | uspto-grants-1978_09 |
| ORD ID | ord-11c17ef93bc840af9442a30d92746ad1 |
| Source note | uspto-grants-1978_09 |