Propargyl bromide → HCID 14876357, compound

HRID 1764072Notes

Reaction equation

HRID 1764072 reaction equation
[CH3:1][C:2]1[S:3][C:4]2[CH:10]=[CH:9][C:8]([O:11][CH2:12][C:13]#[CH:14])=[CH:7][C:5]=2[N:6]=1.[CH2:15]([Br:18])[C:16]#[CH:17]>>[Br-:18].[CH3:1][C:2]1[S:3][C:4]2[CH:10]=[CH:9][C:8]([O:11][CH2:12][C:13]#[CH:14])=[CH:7][C:5]=2[N+:6]=1[CH2:17][C:16]#[CH:15]

Participants

3

Reactant 2

HCID 7842Propargyl bromideHCID 22770068HCID 22770068, compound

Product 1

HCID 14876357HCID 14876357, compoundYield 54.1%

Procedure

20.4 g of 2-methyl-5-propargyloxybenzothiazole and 12.5 g of propargyl bromide were heated on a hot water bath at 80° to 100° C for 3 hours. The precipitated crystals were washed with acetone to give 17.5 g of 2-methyl-3-propargyl-5-propargyloxybenzothiazolium bromide, m.p. 244° C.

Workup

  1. washThe precipitated crystals were washed with acetone

Sources & evidence

ORD record
ord-1c216a920bf640dba0199f66d56e717c
Source dataset
uspto-grants-1978_09
Patent number
US04115122

Reaction notes

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