1-Heptyne → HCID 178442252, compound

HRID 1764080Notes

Reaction equation

HRID 1764080 reaction equation
[CH:1]#[C:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7].[Si]([N:12]=[N+:13]=[N-:14])(C)(C)C>CCOCC>[CH2:5]([C:6]1[N:12]=[N:13][NH:14][CH:7]=1)[CH2:4][CH2:3][CH2:2][CH3:1]

Participants

4

Reactant 2

HCID 123501-HeptyneHCID 78378Azidotrimethylsilane

Product 1

HCID 178442252HCID 178442252, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent2×

Conditions

Temperature
155 °C

Procedure

##STR10## 1-heptyne (9.6 g) and Me3SiN3 (7.8 g) were sealed into a heavy-walled glass reactor at -70° C. and 0.6 mm Hg. The mixture was heated at 155° C. for 48 hrs., cooled and dissolved in Et2O. The Et2O was treated exactly as in Example 2. The product was distilled, bp 89-94/0.2 mm to give 7.2 g (76%) water white liquid whose NMR spectrum and elemental analysis confirm its structure.

Workup

  1. temperature, cooled
  2. distillationThe product was distilled
  3. custom89-94/0.2 mm to give 7.2 g (76%) water white liquid whose NMR spectrum and elemental analysis

Sources & evidence

ORD record
ord-5f5ac48b7bc945e0a0a68eff214fd608
Source dataset
uspto-grants-1978_09
Patent number
US04115288

Reaction notes

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