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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1764092Generated: October 31, 2026

4-Ethylpyridine → 4-Ethylpyridin-2-amine

https://huagongshe.com/reaction/1764092

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-EthylpyridineHCID 10822—
ReactantSodium amideHCID 24533—
Product4-Ethylpyridin-2-amineHCID 118425—

Reaction Steps

This amine is prepared by the method of Case and Kasper from 4-ethylpyridine (Aldrich Chemical) and sodium amide (Fisher Scientific Co.) in 55% molar yield, mp 66°-70° (lit.1 70°-1°).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04115397
Source datasetuspto-grants-1978_09
ORD IDord-74c4f1531618433fb2d7d3a998896f8b
Source noteuspto-grants-1978_09