Phenol, p-(1-cyclohexen-1-yl)- → alpha-[p-(1-Cyclohexenyl)-phenoxy]-undecanoic acid ethyl ester

Beteiligte Stoffe

Reaktionsschritte

To a solution of 1.6 g of sodium in 100 ml of absolute ethanol, 10 g of p-(1-cyclohexenyl)-phenol in a small amount of absolute ethanol are added at room temperature under anhydrous conditions and with stirring. 25.2 Grams of α-bromo-undecanoic acid ethyl ester are then added dropwise. and the reaction mixture is stirred for 24 hours at 50° C. The ethanol is subsequently stripped off in vacuo and the residue is partitioned between water and ice-cold N solution hydroxide solution. The organic phase is washed until neutral, dried over sodium sulphate and concentrated in vacuo. The residue yields the crude α-[p-(1-cyclohexenyl)-phenoxy]-undecanoic acid ethyl ester of the formula ##STR19## in the form of an oil.

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