Hexane → alpha-[p-(1-Cycloheptenyl)-phenoxy]-octanoic acid

HRID 1764148Notes

Reaction equation

HRID 1764148 reaction equation
C([O:3][C:4](=[O:26])[CH:5]([O:12][C:13]1[CH:18]=[CH:17][C:16]([C:19]2[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH:20]=2)=[CH:15][CH:14]=1)[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])C.[OH-].[Na+].CCCCCC>C(O)C>[C:19]1([C:16]2[CH:15]=[CH:14][C:13]([O:12][CH:5]([CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])[C:4]([OH:26])=[O:3])=[CH:18][CH:17]=2)[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH:20]=1

Participants

5

Reactant 3

HCID 8058HexaneHCID 14798Sodium HydroxideHCID 53940125alpha-[p-(1-Cycloheptenyl)-phenoxy]-octanoic acid ethyl ester

Product 1

HCID 20306764alpha-[p-(1-Cycloheptenyl)-phenoxy]-octanoic acid

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Analogously to the process described in Example 2, 13 g of α-[p-(1-cycloheptenyl)-phenoxy]-octanoic acid ethyl ester, on alkaline saponification with 27 ml of 2 N sodium hydroxide solution in 130 ml of ethanol, give α-[p-(1-cycloheptenyl)-phenoxy]-octanoic acid of melting point 59°-60° C (from cold hexane).

Sources & evidence

ORD record
ord-7c871aad059e4a99a7ed5736870f3981
Source dataset
uspto-grants-1978_09
Patent number
US04115416

Reaction notes

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