Glycine → Glycine, N,N-bis(2-cyanoethyl)- (8CI)(9CI)

HRID 1764357Notes

Reaction equation

[C:1](#[N:4])[CH:2]=[CH2:3].[Na].[NH2:6][CH2:7][C:8]([OH:10])=[O:9]>>[C:1]([CH2:2][CH2:3][N:6]([CH2:3][CH2:2][C:1]#[N:4])[CH2:7][C:8]([OH:10])=[O:9])#[N:4]

Participants

Reactant 3

HCID 750Glycine

HCID 7855Acrylonitrile

HCID 5360545Sodium2×

Product 1

HCID 80523Glycine, N,N-bis(2-cyanoethyl)- (8CI)(9CI)

Procedure

Bis-cyanoethyl glycine was prepared in conventional manner by reacting two mols acrylonitrile with one mol sodium salt of glycine in essentially the same manner used in preparing the catalyst of Example 2, except that the sodium salt was neutralized at the end of the reaction.

Sources & evidence

ORD record: ord-f8dcaa48958e420a92f7366218c3aa9c
Source dataset: uspto-grants-1978_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04115634

Reaction notes

Loading…