Benzene → HCID 22768169, compound

HRID 1764402Notes

Reaction equation

HRID 1764402 reaction equation
[CH3:1][C:2]1[O:6][N:5]=[C:4]([N:7]=[C:8]=[O:9])[CH:3]=1.C([OH:13])C=C.[CH:14]1[CH:19]=CC=C[CH:15]=1>>[CH3:1][C:2]1[O:6][N:5]=[C:4]([NH:7][C:8](=[O:13])[O:9][CH2:15][CH:14]=[CH2:19])[CH:3]=1

Participants

4

Reactant 3

HCID 241BenzeneHCID 7858Allyl AlcoholHCID 227681663-Isocyanato-5-methyl-1,2-oxazole

Product 1

HCID 22768169HCID 22768169, compound

Procedure

To a suspension of 5-methyl-3-isoxazolyl isocyanate (1.71 g) in benzene (46 ml), allyl alcohol (0.88 g) is added, and the resultant mixture is refluxed for 3 hours. After cooling, the reaction mixture is evaporated to remove the solvent, whereby allyl N-(5-methyl-3-isoxazolyl)carbamate (2.38 g) is obtained. This substance is recrystallized from cyclohexane to give crystals melting at 76.5° to 77.5° C.

Workup

  1. additionis added
  2. temperatureAfter cooling
  3. customthe reaction mixture is evaporated
  4. customto remove the solvent

Sources & evidence

ORD record
ord-ff552b5166fe4a0680e4cc02b52552fe
Source dataset
uspto-grants-1978_09
Patent number
US04116671

Reaction notes

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