Methanol → HCID 22768409, compound

Participants

Reaction Steps

To a mixture of 26.5 parts of 2-amino-7-methoxy-5-phenyl-3H-1,4-benzodiazepine, 500 parts by volume of methanol and 1.2 parts of glacial acetic acid is added 25 parts of 100% hydrazine hydrate. The mixture is stirred for 1 hour at room temperature and treated in a similar manner to Example 1, whereby 2-hydrazino-7-methoxy-5-phenyl-3H-1,4-benzodiazepine is yielded as crystals melting at 110° C to 120° C.

Provenance & Evidence