Ethanol → HCID 22768399, compound

HRID 1764506Notes

Reaction equation

HRID 1764506 reaction equation
[NH2:1][C:2]1[CH2:8][N:7]=[C:6]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[C:5]2[CH:15]=[C:16]([N+:19]([O-:21])=[O:20])[CH:17]=[CH:18][C:4]=2[N:3]=1.C(O)C.O.[NH2:26]N>C(O)(=O)C>[NH:1]([C:2]1[CH2:8][N:7]=[C:6]([C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:5]2[CH:15]=[C:16]([N+:19]([O-:21])=[O:20])[CH:17]=[CH:18][C:4]=2[N:3]=1)[NH2:26]

Participants

5

Reactant 3

HCID 702EthanolHCID 24654Hydrazine hydrate (1:1)HCID 21265982HCID 21265982, compound

Product 1

HCID 22768399HCID 22768399, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

To a mixture of 5.6 parts of 2-amino-7-nitro-5-phenyl-3H-1,4-benzodiazepine, 200 parts by volume of ethanol and 2.4 parts by volume of glacial acetic acid is added with stirring 5 parts by volume of 80% hydrazine hydrate. The mixture is stirred for 30 minutes at room temperature and treated in a similar manner to Example 1, whereby 2-hydrazino-7-nitro-5-phenyl-3H-1,4-benzodiazepine is yielded as reddish, viscous oily substance.

Workup

  1. additionis added
  2. additiontreated in a similar manner to Example 1

Sources & evidence

ORD record
ord-e978c55c77924c5b93eb49bd3a8e19b9
Source dataset
uspto-grants-1978_09
Patent number
US04116956

Reaction notes

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