Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | 3,5-Dichloro-2-methylthiophene | HCID 12875265 | — |
| Product | HCID 12875270 | HCID 12875270 | — |
Reaction Steps
8.6 G. (0.107 mol) off formalin and 90 ml. of concentrated hydrochloric acid were added to a solution of 10.87 g. (0.065 mol) of 2-methyl-3,5-dichlorothiophene in 45 ml. of acetic acid. The resulting mixture was heated to 70° C. for 18 hrs., cooled, poured into ice water and extracted with ether. The organic solution was washed with water, sodium bicarbonate and water, dried and evaporated to yield 3-chloromethyl-2,4-dichloro-5-methylthiophene as a crude oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04116975 |
|---|
| Source dataset | uspto-grants-1978_09 |
|---|
| ORD ID | ord-47d63f94b621427baf8d509b3ff27918 |
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| Source note | uspto-grants-1978_09 |
|---|
