HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropylamine → 2-n-Butyl-3-[4-(2-hydroxy-3-isopropylaminopropoxy)phenylsulfonyl]benzofuran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropylamine | HCID 6363 | — |
| Reactant | 2-n-Butyl-3-[4-(2,3-epoxypropoxy)phenylsulfonyl]benzofuran | HCID 22768837 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 2-n-Butyl-3-[4-(2-hydroxy-3-isopropylaminopropoxy)phenylsulfonyl]benzofuran | HCID 22768881 | — |
Reaction Steps
2-n-Butyl-3-[4-(2,3-epoxypropoxy)phenylsulfonyl]benzofuran (1.9 g.) was dissolved in 30 ml. of freshly distilled isopropylamine and the solution was heated at 100° for 2 hours. After cooling, the solvent was evaporated to give a residue which was dissolved in chloroform. Evaporation of the solvent gave the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04117128 |
| Source dataset | uspto-grants-1978_09 |
| ORD ID | ord-46ca60b29d5c464db13c4d25eeee43c6 |
| Source note | uspto-grants-1978_09 |