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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1764669Generated: November 1, 2026

4-Methoxybenzenesulfonyl chloride → 2-(4-Chlorophenyl)-3-(4-hydroxyphenylsulfonyl)benzofuran

https://huagongshe.com/reaction/1764669

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxybenzenesulfonyl chlorideHCID 7401—
Reactant2-(4-Chlorophenyl)-1-benzofuranHCID 4368312—
Reactant2-(4-Chlorophenyl)-3-(4-methoxyphenylsulfonyl)benzofuranHCID 22768869—
Product2-(4-Chlorophenyl)-3-(4-hydroxyphenylsulfonyl)benzofuranHCID 22768898—

Reaction Steps

Acylation of 2-(p-chlorophenyl)benzofuran with 4-methoxybenzenesulfonyl chloride as described in Example 1 followed by demethylation of the 2-(4-chlorophenyl)-3-(4-methoxyphenylsulfonyl)benzofuran thus formed also as described therein, gives 2-(4-chlorophenyl)-3-(4-hydroxyphenylsulfonyl)benzofuran.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04117128
Source datasetuspto-grants-1978_09
ORD IDord-8033d638734d4ee5bb74eab89d996bdb
Source noteuspto-grants-1978_09