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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1764671Generated: October 27, 2026

4-Methoxybenzenesulfonyl chloride → 3-(4-Hydroxyphenylsulfonyl)-2-(4-tolyl)benzofuran

https://huagongshe.com/reaction/1764671

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxybenzenesulfonyl chlorideHCID 7401—
Reactant2-(p-Tolyl)benzofuranHCID 638458—
Reactant3-(4-Methoxyphenylsulfonyl)-2-(4-tolyl)benzofuranHCID 22768886—
Product3-(4-Hydroxyphenylsulfonyl)-2-(4-tolyl)benzofuranHCID 22768875—

Reaction Steps

3-(4-Hydroxyphenylsulfonyl)-2-(4-tolyl)benzofuran is prepared by acylation of 2-(4-tolyl)benzofuran with 4-methoxybenzenesulfonyl chloride followed by demethylation of the 3-(4-methoxyphenylsulfonyl)-2-(4-tolyl)benzofuran thus formed as described hereinabove.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04117128
Source datasetuspto-grants-1978_09
ORD IDord-0f92b8fccb4d464da3a1bbaf388ac2f1
Source noteuspto-grants-1978_09