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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1764674Generated: October 26, 2026

4-Methoxybenzenesulfonyl chloride → 2-Ethyl-3-(4-hydroxyphenylsulfonyl)benzofuran

https://huagongshe.com/reaction/1764674

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxybenzenesulfonyl chlorideHCID 7401—
Reactant2-EthylbenzofuranHCID 76582—
Reactant2-Ethyl-3-(4-methoxyphenylsulfonyl)benzofuranHCID 22768874—
Product2-Ethyl-3-(4-hydroxyphenylsulfonyl)benzofuranHCID 22768844—

Reaction Steps

2-Ethyl-3-(4-hydroxyphenylsulfonyl)benzofuran is prepared by acylation of 2-ethylbenzofuran with 4-methoxybenzenesulfonyl chloride followed by demethylation of the 2-ethyl-3-(4-methoxyphenylsulfonyl)benzofuran thus formed as described hereinabove.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04117128
Source datasetuspto-grants-1978_09
ORD IDord-9f32a0fc18aa463a9509877fd137a04e
Source noteuspto-grants-1978_09