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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1764682Generated: October 31, 2026

4-Methoxybenzenesulfonyl chloride → HCID 22768858, compound

https://huagongshe.com/reaction/1764682

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxybenzenesulfonyl chlorideHCID 7401—
ReactantHCID 22768889HCID 22768889—
Reactant2-{[3-(Trifluoromethyl)phenyl]methyl}-1-benzofuranHCID 22768895—
ProductHCID 22768858HCID 22768858—

Reaction Steps

Acylation of 2-(3-trifluoromethylbenzyl)benzofuran with 4-methoxybenzenesulfonyl chloride as described in the procedure described above followed by demethylation of the 3-(4-methoxyphenylsulfonyl)-2-(3-trifluoromethylbenzyl)benzofuran thus formed also as described above gives 3-(4-hydroxyphenylsulfonyl)-2-(3-trifluoromethylbenzyl)benzofuran.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04117128
Source datasetuspto-grants-1978_09
ORD IDord-def9e6f44e5c476289b5eb632c7b77ed
Source noteuspto-grants-1978_09