Thionyl Chloride → HCID 12333890, compound

HRID 1764696Notes

Reaction equation

HRID 1764696 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([S:7]([NH:10][C:11]2[CH:19]=[CH:18][C:14]([C:15](O)=[O:16])=[CH:13][CH:12]=2)(=[O:9])=[O:8])[CH:2]=1.S(Cl)([Cl:22])=O>CN(C)C=O>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([S:7]([NH:10][C:11]2[CH:19]=[CH:18][C:14]([C:15]([Cl:22])=[O:16])=[CH:13][CH:12]=2)(=[O:9])=[O:8])[CH:2]=1

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 22769331HCID 22769331, compound

Product 1

HCID 12333890HCID 12333890, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideCatalyst

Procedure

Into a 500 ml-flask fitted with a mechanical stirrer and a condenser were introduced 26 g (0.093 mol) of 4-(3-pyridylsulfonamido)-benzoic acid and 180 ml of thionyl chloride, after which a few drops of dimethylformamide were added as catalyst. The mixture was progressively heated to boiling, which was maintained for three hours.

Workup

  1. customInto a 500 ml-flask fitted with a mechanical stirrer and a condenser
  2. temperatureThe mixture was progressively heated to boiling, which
  3. temperaturewas maintained for three hours

Sources & evidence

ORD record
ord-3e063e87439a430f895aa42f34400f58
Source dataset
uspto-grants-1978_09
Patent number
US04117151

Reaction notes

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